Anti-Von Willebrand Factor / vWF Antibody (Rabbit Polyclonal antibody) General Information
Anti-Von Willebrand Factor / vWF Antibody
Reacts with: Human
Human Von Willebrand Factor / vWF
Recombinant Human VWF/Von Willebrand Factor Protein (Catalog#10973-H08C)
Produced in rabbits immunized with purified, recombinant Human VWF/Von Willebrand Factor (rh VWF/Von Willebrand Factor; Catalog#10973-H08C; NP_000543.2; Met1-Lys2813). VWF/Von Willebrand Factor specific IgG was purified by Human VWF/Von Willebrand Factor affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunochemical staining of human vwf in human tonsil with rabbit polyclonal antibody at 1:5000 dilution, formalin-fixed paraffin embedded sections.
Immunofluorescence staining of vwf in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human vwf polyclonal antibody (dilution ratio 1:1000) at 4℃ overnight. Then cells were stained with the Alexa Fluor$488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm .
Anti-Von Willebrand Factor / vWF Antibody: Alternative Names
Von Willebrand Factor / vWF Background Information
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.
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