Anti-Von Willebrand Factor / vWF Antibody (Rabbit Polyclonal antibody) General Information
Anti-Von Willebrand Factor / vWF Antibody
Reacts with: Human
Human Von Willebrand Factor / vWF
CHO cell-derived rhvWF (Catalog#10973-H08C)
Produced in rabbits immunized with purified, recombinant Human von Willebrand factor (rhvWF; Catalog#10973-H08C; aa 1-2813; NP_000543.2). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Von Willebrand Factor / vWF Background Information
Von Willebrand Factor (VWF) is a multimeric glycoprotein involved in hemostasis in blood, binds receptors on the surface of platelets and in connective tissue, thereby mediating the adhesion of platelets to sites of vascular injury. From studies it appears that VWF protein uncoils under these circumstances, decelerating passing platelets. VWF protein is deficient or defective in von Willebrand disease (VWD) and is involved in a large number of other diseases, including thrombosis, thrombotic thrombocytopenic purpura, Stroke, Heyde's syndrome, possibly hemolytic-uremic syndrome and so on.
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