SLITL2 / VASN (Protein | Antibody | cDNA Clone | ELISA Kit)

All SLITL2 / VASN reagents are produced in house and quality controlled, including 6 SLITL2 / VASN Antibody, 2 SLITL2 / VASN ELISA, 28 SLITL2 / VASN Gene, 1 SLITL2 / VASN Lysate, 1 SLITL2 / VASN Protein, 1 SLITL2 / VASN qPCR. All SLITL2 / VASN reagents are ready to use.

SLITL2 / VASN Background

Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 1 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall.

SLITL2 / VASN References

  • Gerhard DS, et al. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14(10B):2121-7.
  • Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.
  • Lee KA, et al. (2011) Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. J Biol Chem. 286(48):41530-8.