Bispecific Antibody Production Service

Bispecific Antibody Production Service Description

A bispecific antibody is an artificial antibody containing two kinds of specific antigen binding sites and can establish a bridge between target cells and functional molecules (cells) to stimulate a directed immune response. It is a genetically engineered antibody, which has become a hot spot in the field of antibody engineering, and has a broad application prospect in tumor immunotherapy. Based on the optimized mammalian cell expression platform, Sino Biological can provide you with fast and efficient bispecific antibody expression service.

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Bispecific Antibody Production Service Details

Service procedures Specification Timeline Deliverables Pricing

Gene synthesis and codon optimization (optional)
  1-2 weeks • Purified antibody
• SDS-PAGE data
• CoA

Vector construction
• Expression vector construction
• Plasmid sequencing
• Large scale plasmid production
Expression & purification
1-2 weeks

Expression & purification
• Transient transfection of HEK293 / CHO cells
• Purify the antibody
• Polishing if needed
1-2 weeks

QC analysis
• Analysis by SDS-PAGE and UV
• Purity analysis by HPLC-SEC and endotoxin level analysis (optional)
3 days

In this bispecific antibody production service, please note that:

1.Client needs to provide the antibody sequence or plasmid.
2.A standard service includes: antibody concentration detected by A280 and purity evaluated by SDS-PAGE. If other detection services such as SEC-HPLC and endotoxin level test are required, please indicate it in the request form.

Bispecific Antibody Production Service Highlights

  • Optimized HEK293 or CHO mammalian cell expression platforms:better glycosylation and post-translational modifications
  • Multiple purification methods
    Protein A/G/L affinity purification
    Anion and cation exchange chromatography
    Size Exclusion Chromatography Column (SEC)
  • Powerful QC analysis:SEC-HPLC, MS, activity assay, endotoxin test, glycosylation analysis, etc.

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