TRADD Gene Sequence, Family, Fuction and Expression Information
TRADD cDNA / Gene Overview
TRADD cDNA / gene is a gene with protein product which located on 16q22.1. The TRADD gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 238 organisms have orthologs with human gene TRADD.
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
TRADD cDNA / Gene Sequence
HUMTRADD 1435 bp mRNA linear PRI 26-APR-1996
Homo sapiens TNF receptor-1 associated protein (TRADD) mRNA, 3' end of cds.
This sequence information is just for reference only.
TRADD cDNA / Gene Alias
TRADD cDNA / Gene Expression
Ubiquitous expression in stomach (RPKM 7.8), spleen (RPKM 7.4) and 25 other tissues
Successfully added to cart Please enter catalog numberSubmitted successfullyNetwork ErrorPlease enter your company namePlease enter your namePlease enter your emailPlease enter a valid email addressPlease enter some messageNot found.