Tissue Factor Information: Tissue Factor Protein, Tissue Factor Antibody and Tissue Factor Gene

Tissue Factor Gene family

Tissue Factor Protein

Tissue Factor protein function

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. {ECO:0000269|PubMed:12652293}.

Tissue Factor protein expression

Tissue specificity

Lung, placenta and pancreas.

Induction

TF expression is highly dependent upon cell type. TF can also be induced by the inflammatory mediators interleukin 1 and TNF-alpha, as well as by endotoxin, to appear on monocytes and vascular endothelial cells as a component of cellular immune response.

Tissue Factor protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    295.00
  • Mass (KDa)
    33.00

Tissue Factor Antibody

There are 13 Tissue Factor antibodies which are validated in multiple tissues with various applications, including ELISA, FCM, ICC/IF, WB, IP, ELISA(Cap). There are 9 Tissue Factor antibody for ELISA, 4 Tissue Factor antibody for FCM, 1 Tissue Factor antibody for ICC/IF, 2 Tissue Factor antibody for WB, 1 Tissue Factor antibody for IP, 1 Tissue Factor antibody for ELISA(Cap). Among all these Tissue Factor antibodies, there are 5 anti-Tissue Factor mouse monoclonal antibodies , 2 anti-Tissue Factor rabbit monoclonal antibodies , 6 anti-Tissue Factor rabbit polyclonal antibodies . All the Tissue Factor anbodies are produced in house and all are in stock. Tissue Factor antibody customerized service is available.

Tissue Factor Gene

F3 gene / cDNA is a protein-coding gene which located on 1p21.3. The F3 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog.231 organisms have orthologs with human gene F3.