Sts1 Gene Sequence, Family, Fuction and Expression Information

Sts1 cDNA / Gene Overview

UBASH3B gene / cDNA is a protein-coding gene which located on 11q24.1. The UBASH3B gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, and frog.213 organisms have orthologs with human gene UBASH3B.

Sts1 cDNA / Gene Function

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]

Sts1 cDNA / Gene Sequence

LOCUS NM_032873 6917 bp mRNA linear PRI 21-JUL-2018
Homo sapiens ubiquitin associated and SH3 domain containing B (UBASH3B), transcript variant 1, mRNA.

This sequence information is just for reference only.

Sts1 Family & Reagents

Gene family

Sts1 Gene family reagents (Protein phosphatases)

Approved Symbol Reagent list

Sts1 cDNA / Gene Alias

  • KIAA1959
  • SH3 domain-containing 70 kDa protein
  • suppressor of T-cell receptor signaling 1
  • nm23-phosphorylated unknown substrate
  • STS-1
  • T-cell ubiquitin ligand 2
  • TULA2
  • TULA-2

Sts1 cDNA / Gene Expression

Broad expression in spleen (RPKM 7.0), placenta (RPKM 6.8) and 18 other tissues