ROCK1 Protein Overview: Sequence, Structure, Function and Protein Interaction

ROCK1 Protein Overview

ROCK1 protein family

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

ROCK1 protein name

Recommended name
Rho-associated protein kinase 1
Aliases
p160ROCK
Alternative name
Renal carcinoma antigen NY-REN-35 Rho-associated, coiled-coil-containing protein kinase 1 Rho-associated, coiled-coil-containing protein kinase I p160 ROCK-1

ROCK1 Protein Sequence

Species Human ROCK1 protein
Length 1354
Mass (Da) 158175
Sequence Human ROCK1 protein sequence
Species Mouse ROCK1 protein
Length 1354
Mass (Da) 158171
Sequence Mouse ROCK1 protein sequence
Species Rat ROCK1 protein
Length 1369
Mass (Da) 159626
Sequence Rat ROCK1 protein sequence

ROCK1 Protein Molecular Weight & PI

Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-1354 Rho-associated protein kinase 1.

Molecular weight (Da)

158043.48

Theoretical pI

5.66

ROCK1 Protein Structure

Human RHO-ASSOCIATED PROTEIN KINASE 1 (ROCK 1) IN COMPLEX WITH INDAZOLE DERIVATIVE (COMPOUND 18)
Deposited
2011-12-23   Released:  2012-02-08
Deposition Author(s)
Martin, M.P., Zhu, J.-Yi., Schonbrunn, E.
Organism(s)
Homo sapiens
Expression System
Spodoptera frugiperda
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.2860 Å
R-Value Free
0.236
R-Value Work
0.187
3V8S From PDB

Human ROCK1 protein Secondary structure

ROCK1 Protein Interaction

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