Olig2 Gene Sequence, Family, Fuction and Expression Information
Olig2 cDNA / Gene Overview
OLIG2 gene / cDNA is a protein-coding gene which located on 21q22.11. The OLIG2 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, and frog.156 organisms have orthologs with human gene OLIG2.
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
Olig2 cDNA / Gene Sequence
LOCUS NM_005806 2521 bp mRNA linear PRI 03-JUN-2018
Homo sapiens oligodendrocyte transcription factor 2 (OLIG2), mRNA.
This sequence information is just for reference only.
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