MIG/CXCL9 Protein Overview: Sequence, Structure, Function and Protein Interaction

MIG/CXCL9 Protein Overview

Using a mouse Mig cDNA to screen a cDNA library prepared from cultures of the THP-1 human monocytic cell line that had been treated with interferon-gamma (IFNG; 147570), Farber (1993) identified human MIG. The MIG cDNA predicts a 125-amino acid protein, the first 22 residues of which comprise a signal peptide. The absence of a hydrophobic segment in the mature 103-amino acid protein is consistent with MIG being secreted rather than membrane-bound. MIG was induced in THP-1 cells and in peripheral blood mononuclear cells by interferon-gamma but not by interferon-alpha (147660) or lipopolysaccharide.

MIG/CXCL9 protein family

Belongs to the intercrine alpha (chemokine CxC) family.

MIG/CXCL9 protein name

Recommended name
C-X-C motif chemokine 9
Aliases
crg-10, Humig, SCYB9
Alternative name
Gamma-interferon-induced monokine Monokine induced by interferon-gamma HuMIG MIG Small-inducible cytokine B9

MIG/CXCL9 Gene family protein

MIG/CXCL9 Protein Sequence

Species Human MIG/CXCL9 protein
Length 125
Mass (Da) 14019
Sequence Human MIG/CXCL9 protein sequence
Species Mouse MIG/CXCL9 protein
Length 126
Mass (Da) 14444
Sequence Mouse MIG/CXCL9 protein sequence
Species
Length
Mass (Da)
Sequence

MIG/CXCL9 Protein Molecular Weight & PI

C-X-C motif chemokine 9 precursor (Gamma-interferon-induced monokine) (Monokine induced by interferon-gamma) (HuMIG) (MIG) (Small-inducible cytokine B9) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 23-125 C-X-C motif chemokine 9.

Molecular weight (Da)

11724.81

Theoretical pI

10.34

MIG/CXCL9 Protein Interaction

Recombinant MIG/CXCL9 Protein Feature

MIG/CXCL9 Protein, Human, Recombinant

High Purity
> 90 % as determined by SDS-PAGE
Low Endotoxin
Please contact us for more information.

Recombinant MIG/CXCL9 protein citations

Title
CXCL9 regulates acetaminophen‑induced liver injury via CXCR3
Year
2019
Author
Song, X;Shen, Y;Lao, Y;Tao, Z;Zeng, J;
Journal
Experimental and Therapeutic Medicine
Title
CXCL9 regulates acetaminophen-induced liver injury via CXCR3
Year
2019
Author
Song, X;Shen, Y;Lao, Y;Tao, Z;Zeng, J;Wang, J;Wu, H;
Journal
Exp Ther Med

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