M-CSF Information: M-CSF Protein, M-CSF Antibody and M-CSF Gene

M-CSF Protein

M-CSF protein function

Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. {ECO:0000269|PubMed:16337366, ECO:0000269|PubMed:19934330, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061}.

M-CSF protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

M-CSF Antibody

There are 14 M-CSF antibodies which are validated in multiple tissues with various applications, including FCM, ELISA, ELISA(Cap), ELISA(Det). There are 1 M-CSF antibody for FCM, 10 M-CSF antibody for ELISA, 2 M-CSF antibody for ELISA(Cap), 1 M-CSF antibody for ELISA(Det). Among all these M-CSF antibodies, there are 2 anti-M-CSF mouse monoclonal antibodies , 7 anti-M-CSF rabbit monoclonal antibodies , 5 anti-M-CSF rabbit polyclonal antibodies . All the M-CSF anbodies are produced in house and all are in stock. M-CSF antibody customerized service is available.

M-CSF Gene

CSF1 gene / cDNA is a protein-coding gene which located on 1p13.3. The CSF1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.197 organisms have orthologs with human gene CSF1.