GRP78/HSPA5 Gene Sequence, Family, Fuction and Expression Information

GRP78/HSPA5 cDNA / Gene Overview

HSPA5 gene / cDNA is a protein-coding gene which located on 9q33.3. The HSPA5 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.232 organisms have orthologs with human gene HSPA5.

GRP78/HSPA5 cDNA / Gene Function

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010]

GRP78/HSPA5 cDNA / Gene Sequence

LOCUS
LOCUS NM_005347 3973 bp mRNA linear PRI 12-AUG-2018
DEFINITION
Homo sapiens heat shock protein family A (Hsp70) member 5 (HSPA5), mRNA.
ACCESSION
NM_005347
VERSION
NM_005347.4

This sequence information is just for reference only.

GRP78/HSPA5 Family & Reagents

GRP78/HSPA5 Gene family reagents (Heat shock 70kDa proteins)

Approved Symbol Reagent list
HSPA1A
HYOU1
Approved Symbol Reagent list
HSPA8
   

GRP78/HSPA5 cDNA / Gene Alias

  • BiP
  • glucose-regulated protein
  • 78kDa

GRP78/HSPA5 cDNA / Gene Expression

Broad expression in thyroid (RPKM 442.6), bone marrow (RPKM 284.6) and 24 other tissues