GABARAPL1 Information: GABARAPL1 Protein, GABARAPL1 Antibody and GABARAPL1 Gene

GABARAPL1 Gene family

GABARAPL1 Protein

GABARAPL1 protein function

Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000269|PubMed:16431922, ECO:0000269|PubMed:20404487}.

GABARAPL1 protein expression

Tissue specificity

Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motoneurons in the embryo and in neurons involved in somatomotor and neuroendocrine functions in the adult, particularly in the substantia nigra pars compacta.

GABARAPL1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    117.00
  • Mass (KDa)
    14.00

GABARAPL1 Gene

GABARAPL1 gene / cDNA is a protein-coding gene which located on 12p13.2. The GABARAPL1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and frog.161 organisms have orthologs with human gene GABARAPL1.