CASP8/ALPS2B Protein Overview: Sequence, Structure, Function and Protein Interaction

CASP8/ALPS2B Protein Overview

A cascade of protease reactions is believed to be responsible for the apoptotic changes observed in mammalian cells undergoing programmed cell death. This cascade involves members of the aspartate-specific cysteine proteases of the ICE/CED3 (147678) family, also known as the caspase family.

CASP8/ALPS2B protein family

Belongs to the peptidase C14A family.

CASP8/ALPS2B protein name

Recommended name
Caspase-8
Aliases
Casp-8, FLICE, MACH, MCH5

CASP8/ALPS2B Gene family protein

Death inducing signaling complex

CASP8/ALPS2B Protein Molecular Weight & PI

The parameters have been computed for the following feature

FT CHAIN 217-374 Caspase-8 subunit p18.

Molecular weight (Da)

17902.39

Theoretical pI

5.94

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