CaMKII beta/CAMK2B Gene Sequence, Family, Fuction and Expression Information

CaMKII beta/CAMK2B cDNA / Gene Overview

CAMK2B gene / cDNA is a protein-coding gene which located on 7p13. The CAMK2B gene is conserved in cow, mouse, rat, chicken, zebrafish, and frog.176 organisms have orthologs with human gene CAMK2B.

CaMKII beta/CAMK2B cDNA / Gene Function

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

CaMKII beta/CAMK2B cDNA / Gene Sequence

LOCUS
LOCUS NM_172084 3935 bp mRNA linear PRI 23-JUN-2018
DEFINITION
Homo sapiens calcium/calmodulin dependent protein kinase II beta (CAMK2B), transcript variant 8, mRNA.
ACCESSION
NM_172084
VERSION
NM_172084.2

This sequence information is just for reference only.

CaMKII beta/CAMK2B Family & Reagents

CaMKII beta/CAMK2B Gene family reagents (Calmodulin dependent protein kinases)

Approved Symbol Reagent list
CAMK1
CAMK1G
CAMK4
Approved Symbol Reagent list
CAMK1D
CAMK2A
CAMKV

CaMKII beta/CAMK2B cDNA / Gene Alias

  • calcium / calmodulin-dependent protein kinase type II beta chain
  • CaM kinase II beta subunit
  • CAM2
  • CAMK2
  • CaM-kinase II beta chain
  • proline rich calmodulin-dependent protein kinase

CaMKII beta/CAMK2B cDNA / Gene Expression

Biased expression in brain (RPKM 44.0), heart (RPKM 16.4) and 2 other tissues