CaMKII beta/CAMK2B Gene Sequence, Family, Fuction and Expression Information
CaMKII beta/CAMK2B cDNA / Gene Overview
CAMK2B gene / cDNA is a protein-coding gene which located on 7p13. The CAMK2B gene is conserved in cow, mouse, rat, chicken, zebrafish, and frog.176 organisms have orthologs with human gene CAMK2B.
CaMKII beta/CAMK2B cDNA / Gene Function
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
CaMKII beta/CAMK2B cDNA / Gene Sequence
LOCUS NM_172084 3935 bp mRNA linear PRI 23-JUN-2018
Homo sapiens calcium/calmodulin dependent protein kinase II beta (CAMK2B), transcript variant 8, mRNA.
This sequence information is just for reference only.
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