CALB2 Gene Sequence, Family, Fuction and Expression Information

CALB2 cDNA / Gene Overview

CALB2 cDNA / gene is a gene with protein product which located on 16q22.2. The CALB2 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish, and frog. 196 organisms have orthologs with human gene CALB2.

CALB2 cDNA / Gene Function

This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

CALB2 cDNA / Gene Sequence

LOCUS
X56667 1426 bp mRNA linear PRI 18-APR-2005
DEFINITION
Human mRNA for calretinin.
ACCESSION
X56667
VERSION
X56667.1

This sequence information is just for reference only.

CALB2 Family & Reagents

CALB2 Gene family reagents (EF-hand domain containing)

Approved Symbol Reagent list
SRI
FKBP14
VSNL1
RCN3
CGREF1
FKBP7
S100B
S100A8
GUCA1A
PLS3
Approved Symbol Reagent list
CALU
S100A11
S100A16
S100A2
CETN2
S100A7a
CALML3
S100A6
PVALB
CIB2

CALB2 cDNA / Gene Alias

  • CAL2
  • calretinin

CALB2 cDNA / Gene Expression

Biased expression in fat (RPKM 72.8), testis (RPKM 20.4) and 4 other tissues