ATG10/Apg10 Gene Sequence, Family, Fuction and Expression Information
ATG10/Apg10 cDNA / Gene Overview
ATG10 cDNA / gene is a gene with protein product which located on 5q14.1-q14.2. The ATG10 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and frog. 226 organisms have orthologs with human gene ATG10.
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
ATG10/Apg10 cDNA / Gene Sequence
AK024016 1438 bp mRNA linear PRI 09-JAN-2008
Homo sapiens cDNA FLJ13954 fis, clone Y79AA1001145.
This sequence information is just for reference only.
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