| Title |
PMID |
Year |
Authors |
Journal |
Molecule name |
Catalogue |
| Cryo-EM structure of the human concentrative nucleoside transporter CNT3 |
32776918 |
2020 |
Zhou, Y;Liao, L;Wang, C;Li, J;Chi, P;Xiao, Q;Liu, Q;Guo, L;Sun, L;Deng, D; |
PLoS Biol. |
medium |
SIM SF |
| Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence |
|
2020 |
Chi, X;Jin, X;Chen, Y;Lu, X;Tu, X;Li, X;Zhang, Y;Lei, J;Huang, J;Huang, Z;Zhou, Q;Pan, X; |
Cell Discov |
medium |
SMM TI |
| Molecular insights into the human CLC-7/Ostm1 transporter |
32851177 |
2020 |
Zhang, S;Liu, Y;Zhang, B;Zhou, J;Li, T;Liu, Z;Li, Y;Yang, M; |
Sci Adv |
medium |
SMM293T-I |
| SARS-CoV-2 and three related coronaviruses utilize multiple ACE2 orthologs and are potently blocked by an improved ACE2-Ig |
32847856 |
2020 |
Li, Y;Wang, H;Tang, X;Fang, S;Ma, D;Du, C;Wang, Y;Pan, H;Yao, W;Zhang, R;Zou, X;Zheng, J;Xu, L;Farzan, M;Zhong, G; |
J. Virol. |
|
M293TII |
| Potential host range of multiple SARS-like coronaviruses and an improved ACE2-Fc variant that is potent against both SARS-CoV-2 and SARS-CoV-1 |
|
2020 |
Li, Y;Wang, H;Tang, X;Ma, D;Du, C;Wang, Y;Pan, H; |
bioRxiv |
media |
M293TII |
| Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures |
32134919 |
2020 |
Guan, H;Wang, Y;Yu, T;Huang, Y;Li, M;Saeed, AFUH;Perčulija, V;Li, D;Xiao, J;Wang, D;Zhu, P;Ouyang, S; |
PLoS Biol. |
medium |
MHF1 |
| Molecular basis for regulation of human potassium chloride cotransporters |
|
2020 |
Chi, X;Li, X;Chen, Y;Zhang, Y;Su, Q;Zhou, Q; |
bioRxiv |
medium |
M293TI |
| Structural insights into immunoglobulin M |
32029689 |
2020 |
Li, Y;Wang, G;Li, N;Wang, Y;Zhu, Q;Chu, H;Wu, W;Tan, Y;Yu, F;Su, XD;Gao, N;Xiao, J; |
Science |
medium |
M293TI |
| Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT |
|
2020 |
Yan, R;Li, Y;Shi, Y;Zhou, J;Lei, J;Huang, J;Zhou, Q; |
Sci. Adv. |
medium |
M293TI |
| Structural basis for human TRPC5 channel inhibition by two distinct inhibitors |
|
2020 |
Song, K;Wei, M;Guo, W;Kang, Y;Wu, JX;Chen, L; |
BioRxiv |
medium |
M293TI |
| FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis |
32451436 |
2020 |
Gao, L;Su, C;Du, X;Wang, R;Chen, S;Zhou, Y;Liu, C;Liu, X;Tian, R;Zhang, L;Xie, K;Chen, S;Guo, Q;Guo, L;Hano, Y;Shimazaki, M;Minami, A;Oikawa, H;Huang, N;Houk, KN;Huang, L;Dai, J;Lei, X; |
Nat Chem |
SIM SF |
MSF1 |
| Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor |
32424158 |
2020 |
Guan, C;Niu, Y;Chen, SC;Kang, Y;Wu, JX;Nishi, K;Chang, CCY;Chang, TY;Luo, T;Chen, L; |
Nat Commun |
SIM SF |
MSF1 |
| Systematic identification of chicken type I, II and III interferon-stimulated genes |
32448397 |
2020 |
Dai, M;Xie, T;Liao, M;Zhang, X;Feng, M; |
Vet. Res. |
medium |
M293TI |
| CD3E 蛋白真核表达及全人源 CD3 单克隆抗体的制备 |
|
2020 |
杨希, ;郎巧利, ;黄楠, ;余琳, ;吴梦, ;葛良鹏, ; |
中国免疫学杂志 |
medium |
M293TII |
| Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger Cyclin K degradation |
|
2020 |
Lv, L;Chen, P;Cao, L;Li, Y;Zeng, Z;Cui, Y;Wu, Q;Li, J;Wang, J;Dong, M;Qi, X;Han, T; |
bioRxiv |
|
M293TII |
| Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency |
|
2020 |
Du, S;Cao, Y;Zhu, Q;Wang, G;Du, X;He, R;Xu, H;Zheng, Y;Wang, B;Bai, Y;Ji, C;Yisimayi, A;Wang, Q;Gao, N;Xie, X;Su, X;Xiao, J; |
bioRxiv |
medium |
M293TI |
| Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency |
|
2020 |
Du, S;Cao, Y;Zhu, Q;Wang, G;Du, X;He, R;Xu, H;Zheng, Y;Wang, B;Bai, Y;Ji, C;Yisimayi, A;Wang, Q;Gao, N;Xie, X;Su, X;Xiao, J; |
bioRxiv |
medium |
MSF1 |
| Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency |
|
2020 |
Du, S;Cao, Y;Zhu, Q;Wang, G;Du, X;He, R;Xu, H;Zheng, Y;Wang, B;Bai, Y;Ji, C;Yisimayi, A;Wang, Q;Gao, N;Xie, X;Su, X;Xiao, J; |
bioRxiv |
medium |
MHF1 |
| Structural insights into TSC complex assembly and GAP activity on Rheb |
|
2020 |
Yang, H;Yu, Z;Chen, X;Li, J;Li, N;Cheng, J;Gao, N;Yuan, H;Ye, D;Guan, K;Xu, Y; |
Research Square |
medium |
M293TI |
| Deducing the Crystal Structure of MERS-CoV Helicase |
31883088 |
2020 |
Cui, S;Hao, W; |
Methods Mol. Biol. |
|
MHF1 |
| Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody |
32004500 |
2020 |
Yang, F;Lin, S;Ye, F;Yang, J;Qi, J;Chen, Z;Lin, X;Wang, J;Yue, D;Cheng, Y;Chen, Z;Chen, H;You, Y;Zhang, Z;Yang, Y;Yang, M;Sun, H;Li, Y;Cao, Y;Yang, S;Wei, Y;Gao, GF;Lu, G; |
Cell Host Microbe |
medium |
MSF1 |
| Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody |
32004500 |
2020 |
Yang, F;Lin, S;Ye, F;Yang, J;Qi, J;Chen, Z;Lin, X;Wang, J;Yue, D;Cheng, Y;Chen, Z;Chen, H;You, Y;Zhang, Z;Yang, Y;Yang, M;Sun, H;Li, Y;Cao, Y;Yang, S;Wei, Y;Gao, GF;Lu, G; |
Cell Host Microbe |
medium |
MHF1 |
| Inhibition mechanism of human sterol O-acyltransferase 1 by competitive inhibitor |
|
2020 |
Guan, C;Niu, Y;Chen, SC;Kang, Y;Wu, JX;Nishi, K; |
bioRxiv |
medium |
MSF1 |
| TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels |
31761710 |
2019 |
Jia, Y;Zhao, Y;Kusakizako, T;Wang, Y;Pan, C;Zhang, Y;Nureki, O;Hattori, M;Yan, Z; |
Neuron |
medium |
MSF1 |
| SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability |
31867888 |
2019 |
Rossi, F;Helbling-Leclerc, A;Kawasumi, R;Jegadesan, NK;Xu, X;Devulder, P;Abe, T;Takata, M;Xu, D;Rosselli, F;Branzei, D; |
EMBO Rep. |
medium |
M293TI |
| Cryo-EM Structure of the Human Mitochondrial Translocase TIM22 Complex |
|
2019 |
Qi, L;Wang, Q;Guan, Z;Wu, Y;Cao, J;Zhang, X;Yan, C; |
bioRxiv |
medium |
M293TI |
| Cryo-EM structures of apo and antagonist-bound human Cav3.1 |
31766050 |
2019 |
Zhao, Y;Huang, G;Wu, Q;Wu, K;Li, R;Lei, J;Pan, X;Yan, N; |
Nature |
media |
M293TI |
| LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force |
|
2019 |
Wang, Y;Zhang, C;Shao, S;Liang, L;Sun, Y;Wu, C; |
bioRxiv |
media |
MSF1 |
| Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2 |
30783101 |
2019 |
Dong, J;Du, X;Wang, H;Wang, J;Lu, C;Chen, X;Zhu, Z;Luo, Z;Yu, L;Brown, AJ;Yang, H;Wu, JW; |
Nat Commun |
medium |
SMM 293-TI |
| TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction |
30767704 |
2019 |
You, Z;Xu, Y;Wan, W;Zhou, L;Li, J;Zhou, T;Shi, Y;Liu, W; |
Autophagy |
medium |
SIM SF |
| Piezo-like Gene Regulates Locomotion in Drosophila Larvae |
30726723 |
2019 |
Hu, Y;Wang, Z;Liu, T;Zhang, W; |
Cell Rep |
medium |
SIM SF |
| The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel |
31067468 |
2019 |
Ding, D;Wang, M;Wu, JX;Kang, Y;Chen, L; |
Cell Rep |
|
SMM 293-TI |
| The Antitumor Activity of TCR-Mimic Antibody-Drug Conjugates (TCRm-ADCs) Targeting the Intracellular Wilms Tumor 1 (WT1) Oncoprotein |
31408937 |
2019 |
Shen, Y;Li, YM;Zhou, JJ;Zhou, Z;Xu, YC;Zhao, WB;Chen, SQ; |
Int J Mol Sci |
|
M293TIS |
| Ac25 in Autographa californica multiple nucleopolyhedrovirus was crucial for progeny budded virion production |
31444662 |
2019 |
Guo, Y;Liang, A;Fu, Y; |
Biotechnol. Lett. |
|
MSF1 |
| Structural basis of assembly of the human T cell receptor-CD3 complex |
31461748 |
2019 |
Dong, ;Zheng, L;Lin, J;Zhang, B;Zhu, Y;Li, N;Xie, S;Wang, Y;Gao, N;Huang, Z; |
Nature |
|
SMM 293T-II |
| Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism |
31543422 |
2019 |
Wang, L;Gao, Y;Zheng, X;Liu, C;Dong, S;Li, R;Zhang, G;Wei, Y;Qu, H;Li, Y;Allis, CD;Li, G;Li, H;Li, P; |
Mol. Cell |
|
SMM 293TI |
| The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition |
31553910 |
2019 |
Li, Q;Zhao, Q;Zhang, J;Zhou, L;Zhang, W;Chua, B;Chen, Y;Xu, L;Li, P; |
Cell Rep |
|
SMM 293-TI |
| Affinity maturation of an antibody for the UV-induced DNA lesions 6,4 pyrimidine-pyrimidones |
29749564 |
2018 |
Kong, B;Cao, Y;Wu, D;An, L;Ran, F;Lin, Y;Ye, C;Wang, H;Hang, H; |
Appl. Microbiol. Biotechnol. |
medium |
SMM 293-T1S |
| CD146 interacts with galectin-3 to mediate endothelial cell migration |
29741757 |
2018 |
Zhang, Z;Zheng, Y;Wang, H;Zhou, Y;Tai, G; |
FEBS Lett. |
medium |
SMM-293-TI |
| Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate |
29856959 |
2018 |
Liu, Z;Wang, J;Cheng, H;Ke, X;Sun, L;Zhang, Q;Wang, H; |
Cell |
medium |
SMM 293-TI |
| Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1 |
29567962 |
2018 |
Su, Q;Hu, F;Liu, Y;Ge, X;Mei, C;Yu, S;Shen, A;Zhou, Q;Yan, C;Lei, J;Zhang, Y;Liu, X;Wang, T; |
Nat Commun |
medium |
SMM 293T-I |
| Crystal structures of the extracellular domains of the CrRLK1L receptor-like kinases ANXUR1 and ANXUR2 |
29388293 |
2018 |
Du, S;Qu, LJ;Xiao, J; |
Protein Sci. |
medium |
SIM HF |
| Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3 |
29218514 |
2018 |
Deng, D;Yan, N; |
Methods Mol. Biol. |
medium |
SIM HF |
| Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels |
29594720 |
2018 |
Wu, JX;Ding, D;Wang, M;Kang, Y;Zeng, X;Chen, L; |
Protein Cell |
medium |
SMM-293TI |
| Structure and evolution of the Fam20 kinases |
29572475 |
2018 |
Zhang, H;Zhu, Q;Cui, J;Wang, Y;Chen, MJ;Guo, X;Tagliabracci, VS;Dixon, JE;Xiao, J; |
Nat Commun |
medium |
SIM SF |
| Structure and evolution of the Fam20 kinases |
29572475 |
2018 |
Zhang, H;Zhu, Q;Cui, J;Wang, Y;Chen, MJ;Guo, X;Tagliabracci, VS;Dixon, JE;Xiao, J; |
Nat Commun |
medium |
SIM HF |
| Structure of the human PKD1/PKD2 complex |
|
2018 |
Su, Q;Hu, F;Ge, X;Lei, J;Yu, S;Wang, T;Zhou, Q;Mei, C;Shi, Y; |
Science |
medium |
SMM 293T-I |
| Structure of the intact 14-subunit human cytochrome c oxidase |
30030519 |
2018 |
Zong, S;Wu, M;Gu, J;Liu, T;Guo, R;Yang, M; |
Cell Res. |
medium |
SMM 293-TI |
| Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1 |
30190309 |
2018 |
Pan, X;Li, Z;Zhou, Q;Shen, H;Wu, K;Huang, X;Chen, J;Zhang, J;Zhu, X;Lei, J;Xiong, W;Gong, H;Xiao, B;Yan, N; |
Science |
medium |
SMM 293T-I |
| An OB-fold complex controls the repair pathways for DNA double-strand breaks |
30254264 |
2018 |
Gao, S;Feng, S;Ning, S;Liu, J;Zhao, H;Xu, Y;Shang, J;Li, K;Li, Q;Guo, R;Xu, D; |
Nat Commun |
medium |
SMM 293-TI |
| Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin |
30190470 |
2018 |
Gong, D;Chi, X;Ren, K;Huang, G;Zhou, G;Yan, N;Lei, J;Zhou, Q; |
Nat Commun |
medium |
SMM 293T-I |
| Human SEIPIN Binds Anionic Phospholipids |
30293840 |
2018 |
Yan, R;Qian, H;Lukmantara, I;Gao, M;Du, X;Yan, N;Yang, H; |
Dev. Cell |
medium |
M293TI |
| High cell density fed-batch production of insecticidal recombinant ribotoxin hirsutellin A from Pichia pastoris |
30342541 |
2018 |
Li, H;Xia, Y; |
Microb. Cell Fact. |
medium |
MSF1 |
| Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance |
30389912 |
2018 |
Liang, Y;Tang, H;Guo, J;Qiu, X;Yang, Z;Ren, Z;Sun, Z;Bian, Y;Xu, L;Xu, H;Shen, J;Han, Y;Dong, H;Peng, H;Fu, YX; |
Nat Commun |
medium |
M293TI |
| Ac34 protein of AcMNPV promoted progeny virus production and induced the apoptosis in host Sf9 cells |
30421092 |
2018 |
Zhang, B;Liang, A;Fu, Y; |
Biotechnol Lett |
medium |
MSF1 |
| The Improvement and Application of Lentivirus-Mediated Gene Transfer and Expression System in Penaeid Shrimp Cells |
30542951 |
2018 |
Chen, X;Chen, Y;Shen, X;Zuo, J;Guo, H; |
Mar. Biotechnol. |
medium |
MSF1 |
| Function and Application Analysis of Ac132 Protein in Autographa californica Multiple Nucleopolyhedrovirus |
|
2018 |
Peng, Y;Liang, A;Fu, Y; |
Biotechnol Bioproc E |
medium |
MSF1 |
| An Atomic Structure of the Human Spliceosome |
28502770 |
2017 |
Zhang, X;Yan, C;Hang, J;Finci, LI;Lei, J;Shi, Y; |
Cell |
medium |
M293TI |
| Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation |
28578000 |
2017 |
Kong, L;Yin, H;Yuan, L; |
Biochem. Biophys. Res. Commun. |
medium |
STF01 |
| Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution |
28183995 |
2017 |
Shen, H;Zhou, Q;Pan, X;Li, Z;Wu, J;Yan, N; |
Science |
medium |
M293TI |
| Two dopamine D2-like receptor genes from the silkworm (Bombyx mori) and their evolutionary history in metazoan |
28754962 |
2017 |
Chen, P;Chen, P;Li, T;Shen, Q;Yan, DF;Zhang, L;Chen, X;Li, Y;Zhao, W; |
Sci Rep |
medium |
Opti-MEM I |
| Human microvascular endothelial cell promotes the development of dorsal root ganglion neurons via BDNF pathway in a co-culture system |
28394221 |
2017 |
Yuan, Q;Sun, L;Yu, H;An, C; |
Biosci. Biotechnol. Biochem. |
medium |
MGAI |
| 4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1 |
|
2016 |
Yang, H;Wang, J;Liu, M;Chen, X;Huang, M;Tan, D;Dong, MQ;Wong, CC;Wang, J;Xu, Y;Wang, HW; |
Protein Cell |
medium |
M293TI |
| Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway |
27893712 |
2016 |
Leung, E;Xue, A;Wang, Y;Rougerie, P;Sharma, VP;Eddy, R;Cox, D;Condeelis, J; |
Oncogene |
medium |
MSF1 |
| Functional characterization of human equilibrative nucleoside transporter 1 |
|
2016 |
Huang, W;Zeng, X;Shi, Y;Liu, M; |
Protein Cell |
medium |
M293TI |
| HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains |
|
2016 |
Wang, C;Long, W;Peng, C;Hu, L;Zhang, Q;Wu, A;Zhang, X;Duan, X;Wong, CC;Tanaka, Y;Xia, Z; |
PLoS Pathog. |
medium |
M293TI |
| Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length |
27306797 |
2016 |
Zheng, X;Ramani, A;Soni, K;Gottardo, M;Zheng, S;Ming Gooi, L;Li, W;Feng, S;Mariappan, A;Wason, A;Widlund, P;Pozniakovsky, A;Poser, I;Deng, H;Ou, G;Riparbelli, M;Giuliano, C;Hyman, AA;Sattler, M;Gopalakrishnan, J;Li, H; |
Nat Commun |
medium |
M293TI |
| Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex |
28099411 |
2016 |
Wang, X;Feng, J;Xue, Y;Guan, Z;Zhang, D;Liu, Z; |
Nature |
medium |
MHF1 |
| Crystal structure of the human glucose transporter GLUT1 |
|
2014 |
Deng, D;Xu, C;Sun, P;Wu, J;Yan, C;Hu, M;Yan, N; |
Nature |
medium |
SIM HF |
| Three-dimensional structure of human γ-secretase |
|
2014 |
Peilong Lu#1,3, Xiao-chen Bai#4, Dan Ma#1,3, Tian Xie1,3, Chuangye Yan2,3, Linfeng Sun1,3,Guanghui Yang2,3, Yanyu Zhao1,3, Rui Zhou1,3, Sjors H.W. Scheres
4, and Yigong Shi1,3 |
Nature |
medium |
SMM 293T-I |
