Receptors are proteins, usually cell surface receptors, which bind to ligands and cause responses in the immune system. Receptors can be found in various immune cells like B cells, T cells, NK cells, monocytes and stem cells.
Receptors are bound up with functions such as cell activation, cell adhesion and signaling pathways. These functions play a role with the help of receptors. Cell activation including T cells, dendritic cells, B cells, granulocytes and NK cells, is an important process in innate and adaptive immune system. Receptors on the surface of these cells help complete whole cell activation process. Unlike the receptors that mediate adaptive immunity, the receptors of the innate immunity are typically not clonally distributed; a given set of receptors will be present on all the cells of the same cell type. The binding of pathogens by these receptors gives rise to very rapid responses, which are put into effect without the delay imposed by the clonal expansion of cells needed in the adaptive immune response.
Cells interact with each other, and their substrate, throughout their lifetime. These interactions can be transient, such as at the immunological synapse, or they can be long-lived, such as at a neuromuscular junction. These complex cellular structures involve many proteins; from receptor molecules to structural scaffolding proteins.
Sino Biological offers a comprehensive set of tools for receptors related research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.