Platelet-Derived Growth Factor Receptor/PDGF Receptor

As members of growth factor receptors, platelet-derived growth factor receptors (PDGF receptors) are cell surface receptors that play a crucial role in regulating cell proliferation, cellular differentiation, cell growth, development and many diseases including cancer. There are two forms of PDGF receptor, PDGF α receptor and PDGF β receptor. Constitutive activation of PDGF α receptor or PDGF β receptor is seen in myeloid malignancies as a consequence of fusion to diverse partner genes, and activating mutations of PDGF α receptor are seen in gastrointestinal tumors (GISTs).

pdgf receptor

PDGF Receptor Products List

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PDGFRA/CD140a PDGFRB/CD140b PDGFRL
Receptors
Receptors Classification
What are Receptors
Cytokine Receptors
Growth Factor Receptors+
- Wnt Receptor
- Tie Receptor
- Neurotrophin Receptor
- Ephrin Receptor/Eph Receptor
- Insulin-Like Growth Factor Receptor/IGF Receptor
- Epidermal Growth Factor Receptor/EGF Receptor
- Fibroblast Growth Factor Receptor/FGF Receptor
- Platelet-Derived Growth Factor Receptor/PDGF Receptor
- Vascular Endothelial Growth Factor Receptor/VEGF Receptor
Fc Receptor / FcR
Receptors by Differentiation Cells
Receptors by Functions
Receptors Reagent Products
Receptors by Species