March 2014-Ebola virus disease update, Liberia

23 March 2014

The Ministry of Health (MoH) of Guinea has notified WHO of a rapidly evolving outbreak of Ebola virus disease (EVD) in forested areas of south-eastern Guinea. As of 22 March 2014, a total of 49 cases including 29 deaths (case fatality ratio: 59%) had been reported.

24 March 2014

The Ministry of Health (MoH) of Guinea has notified WHO of a rapidly evolving outbreak of Ebola virus disease (EVD) in forested areas of south-eastern Guinea. As of 24 March 2014, a total of 86 cases including 59 deaths (case fatality ratio: 68.5%) had been reported.

25 March 2014

The Ministry of Health (MoH) of Guinea has notified WHO of a rapidly evolving outbreak of Ebola virus disease (EVD) in forested areas of south-eastern Guinea. As of 25 March 2014, a total of 86 suspected cases including 60 deaths (case fatality ratio: 69.7%) had been reported.

26 March 2014

The total number of suspected cases in the ongoing Ebola virus disease (EVD) outbreak in Guinea remains 86. Two more cases died bringing total deaths to 62 (CFR: 72%). The cases are spread across three districts in south-east Guinea (Guekedou, Macenta, and Kissidougou districts). Seven of the cases are currently undergoing treatment in isolation units in Guekedou district. Investigations on reported cases in Liberia and Sierra Leone along the border with Guinea are ongoing.

Eleven of the reported cases have been confirmed by Institut Pasteur Lyon, France, Institut Pasteur (IP) Dakar, Senegal and Bernhard-Nocht Institute of Tropical Medicine Hamburg, Germany using PCR test.

27 March 2014

The Ministry of Health of Guinea has today reported 4 laboratory confirmed cases of Ebola virus disease (EVD) in the capital, Conakry. In addition, a fifth suspected case died without laboratory confirmation. Intensive case investigations are underway to identify the source and route of these patients' infection, record their travel histories before arrival in Conakry and determine their period of infectivity for the purposes of contact tracing. Rapid Response Teams are carrying out these investigations and sensitizing health care workers and the affected communities about EHF to reduce the risk of further transmission.

The total number of suspected and confirmed cases in the on-going EHF outbreak in Guinea has increased to 103, including 66 deaths. Today 15 new suspected cases were reported in Guinea (8 in Guekedou and 2 in Macenta, in addition to the 5 cases in Conakry). The case fatality rate (CFR) is 64%. All age groups have been affected but most of the cases are adults aged 15-59 years. Four health care workers are among the deaths attributed to the Ebola outbreak. As this is a rapidly changing situation, the number of reported cases and deaths are preliminary and subject to change due to enhanced surveillance activities and laboratory testing of cases.

30 March 2014

As of 28 March, the total number of suspected and confirmed cases in the on-going Ebola virus disease (EVD) outbreak in Guinea has increased to 112, including 70 deaths (Case Fatality Rate 62.5%). New suspected cases have been reported from Conakry (4 cases), Guékédou (4), Macenta (1) and Dabola (1) prefectures. The date of hospital admission of the most recent suspected case is 28 March.

To date 24 clinical samples from Guinea have tested positive by PCR for the ebolavirus in samples from cases in Conakry (11), Guékédou (6) and Macenta (7). In addition, Liberia has reported 2 laboratory confirmed cases in persons who had travelled to Guinea.

Both Sierra Leone and Liberia have revised down the number of suspected cases reported previously. Liberia reported that 3 persons from Guékédou developed symptoms and signs suggestive of EHF and died in Liberia. Pre-mortem samples collected from these cases tested positive for ebolavirus at the Institut Pasteur (IP) Dakar mobile laboratory in Conakry.

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EBOV Viral Molecule
Glycoprotein / EBOV-G
EBOV strain source
Subtype Zaire, strain Mayinga 1976
Subtype Sudan, strain Gulu
Subtype Bundibugyo, strain Bundibugyo 2007
EBOV Infection Receptor
HSPA5
TGF-beta 1 / TGFB1
TGF-beta 2 / TGFB2
TGF-beta 3 / TGFB3
EBOV Infection Associated
ICAM-3 / CD50
DC-SIGN / CD209
TNFA / TNF-alpha
EBOV Information
Ebola virus
What is Ebola virus
Zaire ebolavirus
Sudan ebolavirus
Reston ebolavirus
Tai Forest ebolavirus
Bundibugyo ebolavirus
Ebola virus Outbreak
2014 Ebola virus Outbreak
Ebola virus Disease / Ebola hemorrhagic Fever
Ebola virus Symptom
Ebola virus Infection
Ebola virus Vaccine
Ebola virus Antibody
Ebola virus Antigen
Ebola virus diagnosis
News about Ebola virus
Virus Research Tools
Influenza Virus
EBOV (Ebola Virus)
HIV (Human Immundeficiency Virus)
HCoV (Human Coronavirus)
RSV (Human Respiratory Syncytial Virus)
HCV (Hepatitis C virus)
HPV (Human Paillomavirus)
HCMV (Human Cytomegalovirus)
EV71 (Human Enterovirus 71)
EBV (Epstein-Barr virus)
DENV (Dengue virus )
HeV (Hendra virus )
LASV (Lassa virus)
MARV (Marburgvirus)
NiV (Nipah virus)
RVFV (Rift Valley fever virus)
WNV (West Nile Virus )
PRRSV (Porcne reproductive and respiratory syndrome virus)
SFTSV (Severe fever with thrombocytopenia syndrome bunyavirus )