Interleukin-6 Receptor

Interleukin-6 is a multifunctional cytokine that regulates the immune response, haemopoiesis, the acute phase response and inflammation. IL-6 is produced by various types of cell and influences various cell types, and has multiple biological activities through its unique receptor system. IL-6 exerts its biological activities through two molecules: IL-6R (IL-6 receptor) and gp130. When IL-6 binds to membrane-bound form of IL-6R (mIL-6R), homodimerization of gp130 is induced and a high-affinity functional receptor complex of IL-6, IL-6R and gp130 is formed. Interestingly, soluble form of IL-6R (sIL-6R) also binds with IL-6, and the IL-6-sIL-6R complex can then form a complex with gp130. Interleukin-6 receptor is also known as CD126 (Cluster of Differentiation 126).

interleukin-6 receptor

Interleukin-6 Receptor Products List

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CNTFR G-CSF R/CD114/CSF3R IL11RA/IL-11RA
Il11ra1 IL6R/IL-6R/CD126 IL6ST/gp130/CD130
Interleukin-31 receptor A / IL31RA Leptin Receptor/CD295 LIFR/CD118
OSMR/IL-31RB    
Receptors
Receptors Classification
Cytokine Receptors+
- Chemokine Receptor
- IFN Receptor
- TNF Receptor
- CSF Receptor
- Interleukin Receptor
Interleukin-1 Receptor
Interleukin-6 Receptor
Interleukin-10 Receptor
Interleukin-12 Receptor
Interleukin-17 Receptor
- TGF-beta Superfamily Receptors
Receptors by Differentiation Cells
Receptors by Functions
Receptors Reagent Products
Receptors by Species