CXCL5 Protein

CXCL5 Protein Overview

CXCL5 reagents

Epithelial cell-derived neutrophil-activating peptide ENA78 is an inflammatory chemokine that is produced concomitantly with interleukin-8 (IL8; 146930) in response to stimulation with either interleukin-1 (IL1B; 147720) or tumor necrosis factor-alpha (TNFA; 191160). Chang et al. (1994) identified a full-length ENA78 cDNA and isolated its genomic clone. Rovai et al. (1997) cloned the human ENA78 gene (which is also symbolized SCYB5) as well as GCP2 (SCYB6; 138965). Both coding and noncoding portions of the GCP2 gene share very high nucleotide similarity to ENA78, except for the occurrence of a long interspersed sequence 5-prime of the GCP2 gene. Despite 85% identity of the first 270 nucleotides 5-prime of the transcription start sites, GCP2 and the other CXC chemokine gene ENA78 showed cell-specific differences in regulation.

CXCL5 protein family

Belongs to the intercrine alpha (chemokine CxC) family.

CXCL5 protein name

Recommended name
C-X-C motif chemokine 5
Aliases
ENA-78
Alternative name
ENA-78(1-78) Epithelial-derived neutrophil-activating protein 78 Neutrophil-activating peptide ENA-78 Small-inducible cytokine B5 ENA-78(8-78) ENA-78(9-78)

CXCL5 Gene family protein

CXCL5 Protein Sequence

Species Human CXCL5 protein
Length 114
Mass (Da) 11972
Sequence Human CXCL5 protein sequence
Species Mouse CXCL5 protein
Length 132
Mass (Da) 14235
Sequence Mouse CXCL5 protein sequence
Species Rat CXCL5 protein
Length 130
Mass (Da) 14263
Sequence Rat CXCL5 protein sequence

CXCL5 Protein Molecular Weight & PI

C-X-C motif chemokine 5 precursor (ENA-78(1-78)) (Epithelial-derived neutrophil-activating protein 78) (Neutrophil-activating peptide ENA-78) (Small-inducible cytokine B5) [Contains: ENA-78(8-78); ENA-78(9-78)] Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 37-114 C-X-C motif chemokine 5.

Molecular weight (Da)

8356.87

Theoretical pI

8.81

CXCL5 Protein Structure

Solution structure of CXCL5
Deposited
2013-11-04   Released:  2014-04-02
Deposition Author(s)
Sepuru, K., Rajarathnam, K.
Organism(s)
Homo sapiens
Expression System
Escherichia coli
Experimental Data Snapshot
Method
SOLUTION NMR
2MGS From PDB

Human CXCL5 protein Secondary structure

CXCL5 Protein Interaction

Recombinant CXCL5 Protein Feature

CXCL5 Protein, Human, Recombinant

High Purity
> 95 % as determined by SDS-PAGE
Low Endotoxin
Please contact us for more information.

Bulk Order of Recombinant CXCL5 Protein

Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the website, our customer specialist will get back to you in 24 hours by email.

Custom Recombinant Protein Production Service Features

  • Over 10 years' experience for 6000+ recombinant proteins production.
  • One-stop service from gene synthesis and vector construction to protein expression and purification.
  • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
  • Multiple purification systems (30+) to choose.
  • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
  • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.

Custom Recombinant Protein Production Service Advantages

  • High-efficiency expression vectors
  • High cell density culturing
  • Proprietary medium formulation
  • >6000 proteins expression and purification experience
  • High-efficiency expression vectors
  • High cell density culturing

Recombinant Protein Production Service Description

We offer one-stop services for recombinant protein production using our advanced protein expression platform technologies. Our full services include protein gene synthesis, protein codon optimization, protein expression vector design, large scale cell culture and fermentation, protein purification, and protein quality control testing. We offer significant cost saving advantages and record speed in protein expression and bulk production. We also have extensive experiences and expertise in handling various types of recombinant protein purification projects, with or without purification tags.