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人 CD47 蛋白

產品資料評論實驗方法
反應性: Human  
應用 : ELISA  
    12283-R006-50
    12283-R006-100
    50 µg 
    100 µg 
    Add to Cart
    反應性: Human  
    應用 : ELISA  
      12283-R001-50
      12283-R001-100
      50 µg 
      100 µg 
      Add to Cart
      反應性: Human  
      應用 : ELISA  
        12283-T16-50
        12283-T16-200
        12283-T16-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反應性: Human  
        應用 : ELISA  
          12283-RP01-400
          12283-RP01-200
          12283-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          反應性: Mouse  
          應用 : 
          • Slide 1
          • Slide 1
          101928-T08-50
          101928-T08-200
          101928-T08-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反應性: Rat  
          應用 : ELISA  
            80305-RP01-400
            80305-RP01-200
            80305-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反應性: Rat  
            應用 : ELISA  WB  
            • Slide 1
            80305-T48-50
            80305-T48-200
            80305-T48-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            反應性: Rat  
            應用 : ELISA  
              80305-MM08-50
              80305-MM08-200
              80305-MM08-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart

              HP101891 

              CD47 Recombinant ProteinRelated Products

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              CD47 protein 研究背景

              CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.

              Immune Checkpoint
              Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: WB Antibodies
              Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

              Immunotherapy   Cancer Immunotherapy   Targeted Therapy

               CD47 protein 參考資料
            • Brown EJ, et al. (2001) Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 11(3): 130-5.
            • Oldenborg PA. (2004) Role of CD47 in erythroid cells and in autoimmunity. Leuk Lymphoma. 45(7): 1319-27.
            • Kaczorowski DJ, et al. (2007) Targeting CD47: NO limit on therapeutic potential. Circ Res. 100(5): 602-3.
            • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”