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IL-33 抗體, 兔多抗, 抗原親和純化

產品資料評論實驗方法
描述: Active  
表達宿主: E. coli  
  • Slide 1
10368-HNAE-5
10368-HNAE-20
10368-HNAE-100
5 µg 
20 µg 
100 µg 
Add to Cart
表達宿主: E. coli  
  • Slide 1
70005-DNAE-5
70005-DNAE-20
70005-DNAE-100
5 µg 
20 µg 
100 µg 
Add to Cart

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IL-33 antibody 研究背景

Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial enules), is a proinflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.

 IL-33 antibody 參考資料
  • Iikura M, et al. (2007) IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest. 87(10): 971-8.
  • Lamkanfi M, et al. (2009) IL-33 raises alarm. Immunity. 31(1): 5-7.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”