Text Size:AAA

CCL15 / MIP-5 / MIP-1 delta 抗體, 兔多抗, 抗原親和純化

產品資料評論實驗方法
表達宿主: E. coli  
  • Slide 1
10898-H08E-50
10898-H08E-20
50 µg 
20 µg 
Add to Cart
表達宿主: E. coli  
  • Slide 1
10898-H08E1-50
10898-H08E1-20
50 µg 
20 µg 
Add to Cart

CCL15/MIP-5/MIP-1 delta AntibodyRelated Products

Related Products

Featured Reagent Products

CCL15/MIP-5/MIP-1 delta antibody 研究背景

Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.

 CCL15/MIP-5/MIP-1 delta antibody 參考資料
  • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
  • Youn, et al. (1997) Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3. J Immun. 159: 5201-5.
  • Coulin, et al. (1997) Characterization of macrophage inflammatory protein-5 / human CC cytokine-2, a member of the macrophage-inflammatory-protein family of chemokines. Europ J Biochem. 248: 507-15.
  •  

    CCL15/MIP-5/MIP-1 delta related areas, pathways, and other information

    請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”