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Cbl-c / CBL-3 抗體, 兔多抗, 抗原親和純化

產品資料評論實驗方法
表達宿主: Baculovirus-Insect Cells  
  • Slide 1
15659-H20B-20
15659-H20B-100
20 µg 
100 µg 
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Cbl-c / CBL-3 antibody 研究背景

CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c gene.

 Cbl-c / CBL-3 antibody 參考資料
  • Kim M. et al., 1999, Gene. 239 (1): 145-54.
  • Courbard JR. et al., 2003, J. Biol. Chem. 277 (47): 45267-75.
  • Keane MM. et al., 1999, Oncogene. 18 (22): 3365-75.
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