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KLK7 / Kallikrein 7(PRSS6) 抗體, 兔多抗, 抗原親和純化

產品資料評論實驗方法
描述: Active  
表達宿主: Human Cells  
  • Slide 1
10416-H08H-20
10416-H08H-10
20 µg 
10 µg 
Add to Cart
描述: Active  
表達宿主: Human Cells  
  • Slide 1
50921-M08H-20
50921-M08H-10
20 µg 
10 µg 
Add to Cart

KLK7/Kallikrein 7(PRSS6) AntibodyRelated Products

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KLK7/Kallikrein 7(PRSS6) antibody 研究背景

Kallikrein-7, also known as kallikrein-related peptidase 7, Stratum corneum chymotryptic enzyme, Serine protease 6, KLK7, and PRSS6, is a secreted protein which belongs to the peptidase S1 family and Kallikrein subfamily. Members of the Kallikrein family are involved in various malignancies such as prostate (PSA, KLK2, KLK15), ovarian (KLK4, KLK5, KLK6, KLK8, KLK10), and breast cancer (KLK10, KLK13, KLK14). Kallikrein-7 / KLK7 appears to be increased in ovarian cancer and higher KLK7 expression in ovarian cancer tissue is associated with poorer prognosis of ovarian cancer patients. Kallikrein-7 / KLK7 is abundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Kallikrein-7 / KLK7 is up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at the protein level). It was significantly associated with shorter overall survival (OS) and disease-free survival (DFS). Kallikrein-7 / KLK7 may catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. KLK7 also plays a role in the activation of precursors to inflammatory cytokines.

小鼠 KLK7/Kallikrein 7(PRSS6) antibody 參考資料
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