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VEGF / VEGFA / VEGF165 抗體, 兔多抗, 抗原親和純化

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10009-HNAB-50
10009-HNAB-5
10009-HNAB-20
10009-HNAB-100
10009-HNAB-10
50 µg 
5 µg 
20 µg 
100 µg 
10 µg 
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表達宿主: Human Cells  
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11066-HNAH-500
11066-HNAH-5
11066-HNAH-20
11066-HNAH-100
11066-HNAH-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
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表達宿主: Human Cells  
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10008-HNAH-20
10008-HNAH-10
20 µg 
10 µg 
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表達宿主: Baculovirus-Insect Cells  
  • Slide 1
10008-HNAB-500
10008-HNAB-5
10008-HNAB-20
10008-HNAB-100
10008-HNAB-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
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表達宿主: Baculovirus-Insect Cells  
  • Slide 1
11066-HNAB-500
11066-HNAB-5
11066-HNAB-20
11066-HNAB-100
11066-HNAB-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
表達宿主: Human Cells  
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15692-HNAH-50
15692-HNAH-20
50 µg 
20 µg 
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表達宿主: Baculovirus-Insect Cells  
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50159-MNAB-500
50159-MNAB-5
50159-MNAB-20
50159-MNAB-100
50159-MNAB-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
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表達宿主: Baculovirus-Insect Cells  
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80006-RNAB-5
80006-RNAB-20
80006-RNAB-100
5 µg 
20 µg 
100 µg 
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表達宿主: Human Cells  
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70004-DNAH-20
70004-DNAH-10
20 µg 
10 µg 
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表達宿主: Baculovirus-Insect Cells  
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63004-ZNAB-5
63004-ZNAB-20
63004-ZNAB-100
5 µg 
20 µg 
100 µg 
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HP100106 

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VEGF/VEGFA antibody 研究背景

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

小鼠 VEGF/VEGFA antibody 參考資料
  • Woolard J. et al. (2004) VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Res. 64(21): 7822-7835.
  • Jia SF, et al. (2008) VEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cells. J Exp Ther Oncol. 7(2): 89-97.
  • Cimpean AM, et al. (2008) Vascular endothelial growth factor A (VEGF A) as individual prognostic factor in invasive breast carcinoma. Rom J Morphol Embryol. 49(3): 303-8.
  • Hamdollah Zadeh MA, et al. (2008) VEGF-mediated elevated intracellular calcium and angiogenesis in human microvascular endothelial cells in vitro are inhibited by dominant negative TRPC6. Microcirculation. 15(7): 605-14.
  • Eisenach PA, et al. (2010) MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src. J Cell Sci. 123(Pt 23):4182-4193.
  • Claesson-Welsh L (2010) Gremlin: vexing VEGF receptor agonist. Blood. 116(18):3386-7.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”