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NGF / NGFB 抗體, 兔多抗, 抗原親和純化

產品資料評論實驗方法
描述: Active  
表達宿主: CHO Stable Cells  
  • Slide 1
11050-HNAC-500
11050-HNAC-20
11050-HNAC-100
11050-HNAC-1
500 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
描述: Active  
表達宿主: CHO Stable Cells  
  • Slide 1
50385-MNAC-500
50385-MNAC-5
50385-MNAC-20
50385-MNAC-100
50385-MNAC-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart

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NGF/NGFB/beta-NGF antibody 研究背景

Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

小鼠 NGF/NGFB/beta-NGF antibody 參考資料
  • Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
  • Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
  • Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.
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