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CHL-1 抗體, 兔多抗, 抗原親和純化

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表達宿主: Human Cells  
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10143-H08H-50
10143-H08H-20
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表達宿主: Human Cells  
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51176-MCCH-50
51176-MCCH-20
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表達宿主: Human Cells  
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51176-M02H-50
51176-M02H-20
50 µg 
20 µg 
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表達宿主: Human Cells  
  • Slide 1
51176-M08H-50
51176-M08H-20
50 µg 
20 µg 
Add to Cart

CHL1/LICAM2/CALL AntibodyRelated Products

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CHL1/LICAM2/CALL antibody 研究背景

Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin typeⅢ domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease.

 CHL1/LICAM2/CALL antibody 參考資料
  • Alevizopoulos A, et al. (1997) Regulation of the Transforming Growth Factor beta-responsive Transcription Factor CTF-1 by Calcineurin and Calcium/ Calmodulin-dependent Protein Kinase IV. The Journal of Biological Chemistry. 272: 23597-605.
  • Gerring SL, et al. (1990) The CHL1 (CTF 1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2 / M. EMBO J. 9 (13): 4347-58.
  • Wei MH, et al. (1998) In silico-initiated cloning and molecular characterization of a novel human member of the L1 gene family of neural cell adhesion molecules. Human Genetics. 103 (3): 355-64.
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