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小鼠 PCSK9/NARC1 基因全長cDNA ORF克隆 (表達載體), C-His 標籤

產品資料評論實驗方法
描述: Active  
表達宿主: Human Cells  
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10594-H08H-50
10594-H08H-20
10594-H08H-10
50 µg 
20 µg 
10 µg 
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表達宿主: Human Cells  
  • Slide 1
10594-H08H1-50
10594-H08H1-10
50 µg 
10 µg 
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描述: Active  
表達宿主: Human Cells  
  • Slide 1
50251-M08H-20
50251-M08H-10
20 µg 
10 µg 
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描述: Active  
表達宿主: Human Cells  
  • Slide 1
80005-R08H-20
80005-R08H-10
20 µg 
10 µg 
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描述: Active  
表達宿主: Human Cells  
  • Slide 1
11054-K08H-20
11054-K08H-10
20 µg 
10 µg 
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反應性: Human  
應用 : ELISA  
    10594-MM01-50
    10594-MM01-200
    10594-MM01-100
    50 µg 
    200 µg 
    100 µg 
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    反應性: Human  
    應用 : ELISA  
      10594-T16-50
      10594-T16-200
      10594-T16-100
      50 µg 
      200 µg 
      100 µg 
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      反應性: Human  
      應用 : ELISA  
        10594-RM03-50
        10594-RM03-100
        50 µg 
        100 µg 
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        反應性: Human  
        應用 : ELISA  
          10594-RP02-400
          10594-RP02-200
          10594-RP02-100
          400 µg 
          200 µg 
          100 µg 
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          反應性: Human  
          應用 : ELISA  IHC-P  
          • Slide 1
          10594-T24-50
          10594-T24-200
          10594-T24-100
          50 µg 
          200 µg 
          100 µg 
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          反應性: Human  
          應用 : ELISA  
            10594-RP01-400
            10594-RP01-200
            10594-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反應性: Mouse  
            應用 : ELISA  
              50251-R106-50
              50251-R106-100
              50 µg 
              100 µg 
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              反應性: Mouse  
              應用 : 
              • Slide 1
              • Slide 1
              • Slide 1
              50251-T26-50
              50251-T26-200
              50251-T26-100
              50 µg 
              200 µg 
              100 µg 
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              反應性: Mouse  
              應用 : 
                50251-R214-50
                50251-R214-100
                50251-R214-1
                50 µg 
                100 µg 
                1 mg 
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                反應性: Mouse  
                應用 : ELISA  
                  50251-RP01-400
                  50251-RP01-200
                  50251-RP01-100
                  400 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  反應性: Mouse  
                  應用 : ELISA  
                    50251-RP02-50
                    50251-RP02-200
                    50251-RP02-100
                    50 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    反應性: Rat  
                    應用 : 
                      80005-R007-50
                      80005-R007-100
                      80005-R007-1
                      50 µg 
                      100 µg 
                      1 mg 
                      Add to Cart
                      反應性: Rat  
                      應用 : 
                        80005-MM06-50
                        80005-MM06-200
                        80005-MM06-100
                        80005-MM06-1
                        50 µg 
                        200 µg 
                        100 µg 
                        1 mg 
                        Add to Cart
                        反應性: Rat  
                        應用 : IHC-P  
                        • Slide 1
                        80005-MM04-50
                        80005-MM04-200
                        80005-MM04-100
                        50 µg 
                        200 µg 
                        100 µg 
                        Add to Cart
                        反應性: Rat  
                        應用 : ELISA  
                          80005-RP02-50
                          80005-RP02-200
                          80005-RP02-100
                          50 µg 
                          200 µg 
                          100 µg 
                          Add to Cart
                          反應性: Rat  
                          應用 : ELISA  
                            80005-RP01-400
                            80005-RP01-200
                            80005-RP01-100
                            400 µg 
                            200 µg 
                            100 µg 
                            Add to Cart
                            反應性: Rat  
                            應用 : ELISA  
                              80005-MM03-50
                              80005-MM03-200
                              80005-MM03-100
                              50 µg 
                              200 µg 
                              100 µg 
                              Add to Cart

                              PCSK9/NARC1 ELISA配對抗體

                              檢測限: 47 pg/ml
                              SEK80005-5
                              SEK80005-15
                              5 Plates 
                              15 Plates 
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                              檢測限: 62.5 pg/ml
                              SEK50251-5
                              SEK50251-15
                              5 Plates 
                              15 Plates 
                              Add to Cart

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                              PCSK9/NARC1 cdna-clone 研究背景

                              Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

                              References

                              小鼠 PCSK9/NARC1 cdna-clone 參考資料
                            • Sseidah, N.G. et al., 2003, Proc. Natl. Acad. Sci. USA. 100: 928-933.
                            • Beyer, T.P. et al., 2007, J. Lipid. Res. 48: 1488-1498
                            • Shan, L. et al., 2008, Biochem. Biophys. Res. Commun. 375: 69-73.
                            • Benjannet, S. et al., 2005, J. Biol. Chem. 279: 48865-48875.
                            • Abifadel, M. et al., 2003, Nat. Genet. 34: 154-156.
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