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人 KLK13/Kallikrein 13 基因全長cDNA ORF克隆 (表達載體), C-Flag 標籤

產品資料評論實驗方法
描述: Active  
表達宿主: Human Cells  
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10199-H08H-20
10199-H08H-10
20 µg 
10 µg 
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反應性: Human  
應用 : ELISA  
    10199-MM01-50
    10199-MM01-200
    10199-MM01-100
    50 µg 
    200 µg 
    100 µg 
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    反應性: Human  
    應用 : ELISA  
      10199-R001-50
      10199-R001-100
      50 µg 
      100 µg 
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      反應性: Human  
      應用 : 
        10199-MM06-50
        10199-MM06-200
        10199-MM06-100
        10199-MM06-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
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        反應性: Human  
        應用 : ELISA  
          10199-T16-50
          10199-T16-200
          10199-T16-100
          50 µg 
          200 µg 
          100 µg 
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          反應性: Human  
          應用 : ELISA  
            10199-RP02-50
            10199-RP02-200
            10199-RP02-100
            50 µg 
            200 µg 
            100 µg 
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            反應性: Human  
            應用 : ELISA  
              10199-RP01-400
              10199-RP01-200
              10199-RP01-100
              400 µg 
              200 µg 
              100 µg 
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              KLK13/Kallikrein 13 cdna-clone 研究背景

              Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.

               KLK13/Kallikrein 13 cdna-clone 參考資料
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