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PIGR / Poly-Ig receptor 抗體, 兔多抗

產品資料評論實驗方法
描述: Active  
表達宿主: Human Cells  
  • Slide 1
10131-H08H-50
10131-H08H-100
50 µg 
100 µg 
Add to Cart
描述: Active  
表達宿主: Human Cells  
  • Slide 1
50119-M08H-50
50119-M08H-100
50 µg 
100 µg 
Add to Cart

PIGR ELISA配對抗體

檢測限: 7.81 pg/ml
SEK50119-5
SEK50119-15
5 Plates 
15 Plates 
Add to Cart
檢測限: 62.5 pg/ml
SEK10131-5
SEK10131-15
5 Plates 
15 Plates 
Add to Cart

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PIGR antibody 研究背景

Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.

 PIGR antibody 參考資料
  • Coyne, R. S. et al., 1995, J. Biol. Chem. 269 (50) :31620-31625. 
  • Kaetzel,C.S., 2001,  Curr Biol. 11(1): R35-38.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”