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人 BPHL 基因全長cDNA ORF克隆 (表達載體), N-His 標籤

產品資料評論實驗方法
表達宿主: E. coli  
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13675-H07E-20
13675-H07E-100
20 µg 
100 µg 
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反應性: Human  
應用 : ELISA  WB  IHC-P  IP  
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13675-T60-50
13675-T60-200
13675-T60-100
50 µg 
200 µg 
100 µg 
Add to Cart

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BPHL cdna-clone 研究背景

BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. BPHL also activates valacyclovir to acyclovir. It may play a role in detoxification processes.

 BPHL cdna-clone 參考資料
  • Lai L. et al., 2008, J Biol Chem. 283 (14): 9318-27.
  • Davila S. et al., 2010, Genes Immun. 11 (3): 232-8.
  • Hendrickson SL. et al., 2010, PLoS One. 5 (9): e12862.
  • 請注意:所有產品都是“僅用於科研,而不能用於診斷或治療用途”