PSMA Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag


PSMA Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: General Information

NCBI Ref Seq
RefSeq ORF Size
2253 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence (Nucleotide may contain silent mutation without changing amino acid sequence)
Full length Clone DNA of Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1.
Enhanced CMV mammalian cell promoter
Tag Sequence
Sequencing Primers
Quality Control
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains 10μg lyophilized plasmid
The lyophilized plasmid can be stored at room temperature for three months

PSMA Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: Synonyms

FGCP cDNA ORF Clone, Human; FOLH cDNA ORF Clone, Human; GCP2 cDNA ORF Clone, Human; GCPII cDNA ORF Clone, Human; mGCP cDNA ORF Clone, Human; NAALAD1 cDNA ORF Clone, Human; NAALAdase cDNA ORF Clone, Human; PSM cDNA ORF Clone, Human; PSMA cDNA ORF Clone, Human

PSMA Background Information

Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.
Full Name
folate hydrolase (prostate-specific membrane antigen) 1
  • Israeli R.S., et al.,(1993), Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen. Cancer Res. 53:227-230.
  • Su S.L., et al., (1995), Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression.Cancer Res. 55:1441-1443.
  • O'Keefe D.S., et al.,(1998), Mapping, genomic organization and promoter analysis of the human prostate-specific membrane antigen gene.Biochim. Biophys. Acta 1443:113-127.
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