TNFAIP3, also named A2, uses ubiquitin-related functions to regulate immune activation, deficiency of which is highly related to autoimmune disease. Mutations in tumor necrosis factor alpha-induced protein 3 (TNFAIP3), a key player in the negative feedback regulation of nuclear factor-kappaB signaling, have recently been recognized as leading to early onset autoinflammatory and autoimmune syndrome.
tumor necrosis factor, alpha-induced protein 3
A20/TNFAIP3 cDNA ORF Clone, Human, Related Products
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