VEGFD Proteins, Antibodies, cDNA Clones Research Reagents

All VEGFD reagents are produced in house and quality controlled, including 6 VEGFD Antibody, 39 VEGFD Gene, 6 VEGFD Lysate, 6 VEGFD Protein, 3 VEGFD qPCR. All VEGFD reagents are ready to use.

VEGFD Protein (6)

    VEGFD Antibody (6)

      VEGFD cDNA Clone (39)

      NM_004469.2
      NM_010216.1
      AY032728.1

      VEGFD Lysate (6)

        VEGFD Background

        Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.

        VEGFD References

        • Avantaggiato V, et al. (1998) Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family. Mech Dev. 73(2):221-4.
        • Rocchigiani M, et al. (1998) Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes. Genomics 47(2):207-16.
        • Karpanen T, et al. (2008) VEGF-D: a modifier of embryonic lymphangiogenesis. Blood. 112(5): 1547-8.

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