SOCS6 Antibodies, cDNA Clones Research Reagents

SOCS6 (Suppressor Of Cytokine Signaling 6) is a protein coding gene located on human chromosome 18q22.2. SOCS6 is also known as CIS4, SSI4, CIS-4, SOCS4, STAI4, SOCS-4, SOCS-6, STATI4 and HSPC060. The human SOCS6 gene encodes a 59528 Da protein containing 535 amino acids. The SOCS6 protein is ubiquitously expressed in small intestine, colon and other tissues. Among its related pathways are Signaling by GPCR and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. SOCS6 is related to protein kinase inhibitor activity. SOCS7 is an important paralog of SOCS6 gene. SOCS6 is associated with some diseases, including Somatization Disorder and Articulation Disorder.

SOCS6 Antibody (1)

    SOCS6 cDNA Clone (15)

    SOCS6 qPCR Primer (1)

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    SOCS6 Background

    Suppressor of cytokine signaling (SOCS) is a family of cytokine-inducible negative regulators of cytokine signaling and it plays a crucial role in various physiological processes. The overexpression of SOCS6 inhibited PCa cell invasion, migration, tumor xenografts growth and angiogenesis, but induced PCa cell apoptosis (P values <0.05). the reduced expression of SOCS6 may be predictive of unfavorable prognosis in PCa. Thus, SOCS6 may serves as a tumor suppressor and a novel therapeutic target for this cancer.

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