SLITL2/VASN Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

VASN (Vasorin) is a protein coding gene located on human chromosome 16p13.3. VASN is also known as SLITL2. The human VASN gene encodes a 71713 Da protein containing 673 amino acids. The VASN protein is broadly expressed in placenta, kidney and other tissues. VASN is related to transforming growth factor beta binding. TLR7 is an important paralog of VASN gene. VASN is associated with some diseases, including Brain Oligodendroglioma and Hematuria, Benign Familial.

SLITL2/VASN Protein (1)

    SLITL2/VASN Antibody (7)

      SLITL2/VASN ELISA Kit & Match Antibody ELISA Pair Set (2)

      SLITL2/VASN cDNA Clone (28)

      BC068575
      NM_139307.3
      NM_001109382.1

      In cloning vector

      In lentiviral vector

      SLITL2/VASN qPCR Primer (1)

      SLITL2/VASN Lysate (1)

        SLITL2/VASN Background

        Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall.

        SLITL2/VASN References

        • Gerhard DS, et al. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14(10B):2121-7.
        • Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.
        • Lee KA, et al. (2011) Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. J Biol Chem. 286(48):41530-8.

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