SerpinB8 Proteins, Antibodies, cDNA Clones Research Reagents

All SerpinB8 reagents are produced in house and quality controlled, including 3 SerpinB8 Antibody, 30 SerpinB8 Gene, 1 SerpinB8 IP Kit, 1 SerpinB8 Lysate, 1 SerpinB8 Protein, 2 SerpinB8 qPCR. All SerpinB8 reagents are ready to use.

SerpinB8 Protein (1)

    SerpinB8 Antibody (3)

      SerpinB8 cDNA Clone (30)

      SerpinB8 Lysate (1)

        SerpinB8 Background

        Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.
        Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional diagnostic immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.

        SerpinB8 References

        • Sumi, Y. et al., 1989, J. Biochem. 106: 703-7.
        • Rawlings, N.D. et al., 2004, Biochem J. 378: 705-16.
        • Gillard, A. et al., 2006, Am J Nephrol. 26 (1): 34-42.
        • Filleur, S. et al., 2009, J Cell Biochem. 106 (5): 769-75.
        • de Koning, P.J. et al., 2009, Pancreas. 38 (4): 461-7.

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