PKC alpha/PRKCA Antibodies, cDNA Clones Research Reagents

PRKCA (Protein Kinase C Alpha) is a protein coding gene located on human chromosome 17q24.2. PRKCA is also known as AAG6, PKCA, PRKACA, PKCI+/-, PKCalpha and PKC-alpha. The human PRKCA gene encodes a 76750 Da protein containing 672 amino acids. The PRKCA protein is ubiquitously expressed in brain, adrenal and other tissues. Among its related pathways are DAG and IP3 signaling and Regulation of activated PAK-2p34 by proteasome mediated degradation. PRKCA is related to transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. PRKCB is an important paralog of PRKCA gene. PRKCA is associated with some diseases, including Chordoid Glioma and Papillary Glioneuronal Tumors.

PKC alpha/PRKCA Antibody (1)

    PKC alpha/PRKCA cDNA Clone (15)

    PKC alpha/PRKCA qPCR Primer (1)

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    PKC alpha/PRKCA Background

    Protein kinase C alpha (PRKCA) is involved in multiple functions and has been implicated in heart failure risks and treatment outcomes. The protein kinase C alpha (PRKCA) gene, coding for a Th17-cell-selective kinase, shows a complex splicing pattern, with at least 2 stable alternative transcripts characterized by an alternative upstream polyadenylation site. Polymorphisms in this gene were associated with several conditions, including multiple sclerosis, asthma, schizophrenia, and cancer. The protein kinase C alpha (PRKCA) gene, encoding a Th17-cell-selective kinase, was repeatedly associated with multiple sclerosis (MS).PRKCA polymorphisms and gene-gene interactions within the ACEi pathway affect the antihypertensive responses to enalapril.

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