Neurotrophin 3 Proteins, Antibodies, cDNA Clones Research Reagents

NTF3 (Neurotrophin 3, also known as NT3; HDNF; NGF2; NT-3; NGF-2), located on 12p13.31, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The gene produces a 29355 Da protein composed of 257 amino acids. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. Diseases such as Hypochondriasis and Demyelinating Disease are associated with NTF3. The related pathways of NTF3 include the NF-KappaB Family Pathway and Activation of cAMP-Dependent PKA.

Neurotrophin 3 Protein (1)

    Neurotrophin 3 Antibody (1)

      Neurotrophin 3 cDNA Clone (26)

      NM_002527.4
      NM_008742.2

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      Neurotrophin 3 Background

      NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.

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