NAMPT Proteins, Antibodies, cDNA Clones Research Reagents

All NAMPT reagents are produced in house and quality controlled, including 1 NAMPT Antibody, 17 NAMPT Gene, 1 NAMPT IP Kit, 1 NAMPT Lysate, 1 NAMPT Protein, 1 NAMPT qPCR. All NAMPT reagents are ready to use.

NAMPT Protein (1)

    NAMPT Antibody (1)

      NAMPT cDNA Clone (17)


      In cloning vector

      In lentiviral vector

      NAMPT qPCR Primer (1)

      NAMPT Lysate (1)

        NAMPT Background

        Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is also considered as an essential enzyme mediating granulocyte colony-stimulating factor (G-CSF)-triggered granulopoiesis in healthy individuals and in individuals with severe congenital neutropenia. Intracellular NAMPT and NAD+ amounts in myeloid cells, as well as plasma NAMPT and NAD+ levels, were increased by G-CSF treatment of both healthy volunteers and individuals with congenital neutropenia.

        NAMPT References

        • Skokowa J, et al. (2009) NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD+-sirtuin-1-dependent pathway. Nat Med. 15(2): 151-8.
        • Samal B, et al. (1994) Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Mol Cell Biol. 14 (2): 1431-7.

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