MMP13 Antibodies, cDNA Clones Research Reagents

All MMP13 reagents are produced in house and quality controlled, including 2 MMP13 Antibody, 29 MMP13 Gene, 1 MMP13 qPCR. All MMP13 reagents are ready to use.

MMP13 Antibody (2)

    MMP13 cDNA Clone (29)

    NM_002427
    BC067522

    In lentiviral vector

    NM_008607.2
    NM_133530.1

    In cloning vector

    In lentiviral vector

    MMP13 qPCR Primer (1)

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    MMP13 Background

    Matrix metalloproteinases (MMPs) such as MMP13 promote tumour growth and progression by mediating extracellular matrix (ECM) reorganization and regulating the biological activity of cytokines.Matrix metalloproteinase 13 (MMP13) plays a central role in the MMP activation cascade that enables degradation of the extracellular matrix and basement membranes, and it is identified as a potential driver in oral carcinogenesis.MMP13 is enriched in mature chondrocytes and considered a prime cause of ECM degradation in the osteoarthritic articular cartilage in temporomandibular joints. A missense mutation of MMP13 causes the Missouri type of human spondyloepimetaphyseal dysplasia (SEMD(MO)), an autosomal dominant disorder characterized by defective growth and modeling of vertebrae and long bones.

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