MEK3/MKK3 Antibodies, cDNA Clones Research Reagents

MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3, also known as MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2), located on 17p11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, and mosquito. The gene produces a 39318 Da protein composed of 347 amino acids. The protein encoded by this gene is a dual-specificity protein kinase that belongs to the MAP kinase kinase family. Diseases such as Inhalation Anthrax and Cutaneous Anthrax are associated with MAP2K3. The related pathways of MAP2K3 include Integrin Pathway and HIF1Alpha Pathway.

MEK3/MKK3 Antibody (2)

    MEK3/MKK3 cDNA Clone (18)

    NM_002756.4

    In expression vector

    NM_001100674.1

    In cloning vector

    In lentiviral vector

    MEK3/MKK3 qPCR Primer (1)

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    MEK3/MKK3 Background

    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3, also known as MKK3) is a Protein Coding gene. The protein encoded by this gene is a dual-specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress and participates in the MAP kinase-mediated signaling cascade. 3 alternatively spliced human isoforms have been reported. MAP2K3 is widely expressed in bone marrow, gall bladder, and other tissues. MAP2K3 resides in a biological pathway linked to memory. It is in a signaling cascade associated with beta-amyloid mediated apoptosis and has enriched expression in microglia.MAP2K3 may represent a novel therapeutic target for age-related memory decline and perhaps Alzheimer's disease (AD).

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