MASP2 Antibodies, cDNA Clones Research Reagents

MASP2 (Mannan Binding Lectin Serine Peptidase 2) is a protein coding gene located on human chromosome 1p36.22. MASP2 is also known as sMAP, MAP19, MASP-2 and MASP1P1. The human MASP2 gene encodes a 75702 Da protein containing 686 amino acids. The MASP2 protein is biasedly expressed in liver, bone marrow and other tissues. Among its related pathways are Innate Immune System and Complement and coagulation cascades. MASP2 is related to calcium ion binding and peptidase activity. MASP1 is an important paralog of MASP2 gene. MASP2 is associated with some diseases, including Masp2 Deficiency and Rheumatic Fever.

MASP2 Antibody (1)

    MASP2 cDNA Clone (1)


    In expression vector

    MASP2 Background

    MASP-2 is the serine protease responsible for lectin pathway activation.MASP-2 is a key protein of the lectin pathway of complement system. Several MASP2 polymorphisms were associated with MASP-2 serum levels or functional activity. The gene MASP2 (mannan-binding lectin (MBL)-associated serine protease 2) encodes two proteins, MASP-2 and MAp19 (MBL-associated protein of 19 kDa), bound in plasma to MBL and ficolins.

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