LYPD3 Proteins, Antibodies, cDNA Clones Research Reagents

All LYPD3 reagents are produced in house and quality controlled, including 6 LYPD3 Antibody, 26 LYPD3 Gene, 2 LYPD3 Lysate, 2 LYPD3 Protein, 2 LYPD3 qPCR. All LYPD3 reagents are ready to use.

LYPD3 Protein (2)

    LYPD3 Antibody (6)

      LYPD3 cDNA Clone (26)


      LYPD3 Lysate (2)

        LYPD3 Background

        Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4 and LYPD3, is a cell membrane protein which contains twoUPAR/Ly6 domains. Human LYPD3 contains twoUPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression

        LYPD3 References

        • Smith B.A., et al., 2001, Cancer Res. 61:1678-85.
        • Wuerfel J., et al., 2001, Gene 262:35-41.
        • Clark H.F., et al., 2003, Genome Res. 13:2265-70.
        • Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-85.
        • Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-57.

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