LILRA3 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All LILRA3 reagents are produced in house and quality controlled, including 6 LILRA3 Antibody, 1 LILRA3 ELISA, 13 LILRA3 Gene, 2 LILRA3 Lysate, 3 LILRA3 Protein, 1 LILRA3 qPCR. All LILRA3 reagents are ready to use.

LILRA3 Protein (3)

    LILRA3 Antibody (6)

      LILRA3 ELISA Kit & Match Antibody ELISA Pair Set (1)

      LILRA3 cDNA Clone (13)

      BC028208

      LILRA3 qPCR Primer (1)

      LILRA3 Lysate (2)

        LILRA3 Background

        ILT6, also known as LILRA3, belongs to the ILT family. In human, the ILT gene family includes up to 11 members. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT6 lacks a transmembrane domain. The function of ILT6 is currently unknown. however it is highly homologous to other LILR genes, and can bind human leukocyte antigen (HLA) class I. Therefore, if secreted, the ILT6 might impair interactions of membrane-bound LILRs (such as LILRB1, an inhibitory receptor expressed on effector and memory CD8 T cells) with their HLA ligands, thus modulating immune reactions and influencing susceptibility to disease.

        LILRA3 References

        • Wi?niewski A, et al. (2004) Distribution of LILRA3 (ILT6 / LILRA3/LIR4) deletion in psoriatic patients and healthy controls. Hum Immunol. 64(4):458-61.
        • Norman PJ, et al. (2003) DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3. Immunogenetics. 55(3):165-71.
        • Cella M, et al. (1997) A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med. 185(10): 1743-51.

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