Lamin B1/LMNB1 Antibodies, cDNA Clones Research Reagents

All Lamin B1/LMNB1 reagents are produced in house and quality controlled, including 1 Lamin B1/LMNB1 Antibody, 30 Lamin B1/LMNB1 Gene. All Lamin B1/LMNB1 reagents are ready to use.

Lamin B1/LMNB1 Antibody (1)

    Lamin B1/LMNB1 cDNA Clone (30)

    Lamin B1/LMNB1 Background

    Duplication of the LMNB1 gene encoding lamin B1 causes adult-onset autosomal-dominant leukodystrophy (ADLD) starting with autonomic symptoms, which are followed by pyramidal signs and ataxia. LMNB1 functions in nuclear envelope lamina and possesses a transcriptional coregulatory activity having an important role in DNA replication, cellular aging, and stress responses. Clinically, the expression level of lamin B1 correlated positively with tumor stages, tumor sizes, and number of nodules.

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